Thursday, 23 February 2012

Public Health Officials-Public Health Issue-Survival Instincts-Human Emotion-Animals

Improper Condom Use A Public Health Issue Worldwide

Problems with the correct use of the male condom, such as not wearing a condom throughout sex or putting it on upside down, are common in the U.S. and have become a major concern of public health officials. New research shows that countries around the world are facing similar challenges... read more..


Understanding Human Emotions Via Animals' Survival Instincts

Can Animals' survival instincts shed additional light on what we know about human emotion? New York University neuroscientist Joseph LeDoux poses this question in outlining a pioneering theory, drawn from two decades of research, that could lead to a more comprehensive understanding of emotions in both humans and animals... read more..

Cranberry Juice-Sugary Drinks-Calories

Yikes... There are 137 calories in 8 oz of cranberry juice just from sugar! You...

Yikes... There are 137 Calories in 8 oz of cranberry juice just from Sugar! You won't believe how much sweet stuff these other drinks pack.5 Super Sugary Drinks to Avoid | Fitbiefitbie.msn.comCheck out which surprisingly calorie- loaded liquids have been flying under your radar read more..

Young People-Hiv Status

More than 3,600 young people have signed up to update their HIV...

More than 3,600 young people have signed up to update their HIV status through the “Update Your Status” campaign run by our friends atDo Something. If you live in the U.S. and are 25 or under, you can join the movement by signing on, getting tested and passing the message along to your friends. Refer 5 of your friends and you could win a $500 scholarship! Best of all, you’ll have done something great for your health and the health of your community. Go to: http://www.dosomething.org/status read more..

Reproductive Biology-Medical Breakthrough-Funding Agencies-Opera Experiment-Infertile Women

Tunisia: Medical Breakthrough Brings Hope to Infertile Women

[Tunisia Live] Dr. Elyess Mkaddem, a Tunisian specialist in reproductive biology, has announced the birth of the first baby in Tunisia to be conceived through a revolutionary new procedure know as embryo vitrification. read more..


OPERA experiment reports anomaly in flight time of neutrinos from CERN to Gran Sasso

The OPERA Collaboration has informed its funding agencies and host laboratories that it has identified two possible effects that could have an influence on its neutrino timing measurement. These both require further tests with a short pulsed beam. If confirmed, one would increase the size of the measured effect, the other would diminish it. read more..

Whole Grains-Sneak

Want to feel fuller, eat less, and flatten your belly in the process? Sneak in s...

Want to feel fuller, eat less, and flatten your belly in the process? Sneak in some extra Whole Grains! (Brought to you by Quaker)6 Surprising Ways to Sneak in Whole Grains | Fitbiefitbie.msn.comGive your next meal a belly-flattening, heart-healthy makeover with these super simple suggestions read more..

Hiv Positive-Hiv Negative-Condoms-Arvs-HIV

Wagging Fingers Hasn't Worked; Let's Try Pills

It is very reassuring that a commentator in Kenya has mentioned, albeit briefly, that providing ARVs to HIV negative people will strain resources in a country where it is not even possible to supply all HIV positve people with them.Many people don't have food, water, cheap drugs for everyday, but deadly, diseases, contraception and family planning, proper education, infrastructure, and a great many other things. Why the obsession with grossly overpriced drugs that will not make any material differenc to most people's health?But there are some odd remarks in the article. One person mentioned in the article that she had not had sex with her husband for the first three years after finding out that he was HIV positive. Then she started to use Condoms.So far so good. Condoms give a good level of protection if they are used properly and used all the time. There are all sorts of stories about condoms breaking but this should be rare if people really know how to use them properly. And at least condoms are cheap and have other benefits, protecting against sexually transmitted infections and preventing unplanned pregnancies.But the article is about using drugs to reduce HIV transmission. This would be in the form of pre-exposure prophylaxis (PrEP), where a HIV negative person takes an antiretroviral drug regularly to reduce the probability of being infected, or 'treatment as prevention', where the HIV positive person takes ARVs which reduce the viral load to a level where HIV is a lot less likely to be transmitted.If condoms are used, is the risk that the HIV negative partner faces going to be reduced further when they also take PrEP? Perhaps so, perhaps a belt and braces policy gives more protection.But if the HIV positive partner is on ARVs, taking them correctly, responding to them (to the extent that their viral load is low, etc), does the HIV negative partner need to be taking PrEP? Couldn't the HIV negative partner just make sure that condoms are used?The more important questions are about whether there will be enough money for all HIV positive people to receive the drugs and other care they need, as well as for HIV negative people to receive the most effective prevention assistance available.Currently, only 20-40% of people in need of ARVs are receiving them. Will the need for PrEP be given priority over the need for ARVs, given that PrEP is for people who are healthy and normal ARV treatment is for people who are sick and will die without the drugs?But even 'treatment as prevention' is not that straightforward. The majority of people in most African countries do not know their HIV status. Even the majority of HIV positive people do not know their status. How easy will it be to identify all HIV positive people and keep on identifying new infections for as long as they occur.Apparently Swaziland is going to test its entire population and put everyone found to be HIV positive on ARVs, effectively, 'treatment as prevention' or 'test and treat'. There are only 1.2 million Swazis but an estimated 200,000 of them are HIV positive.Yet only about 60,000 HIV positive Swazis are on ARVs and the country doesn't even have enough supplies for them. Similar shortages have occurred in other African countries. Health services can barely cope with keeping a fraction of people on treatment, let alone all those who need them.The Kenyan article continues with the sort of honesty that you wouldn't normally find in an article about HIV: prevention so far has had little impact and the rate of new infections is still very high; sexual behavior change, the main aim of most prevention programs, has not occurred to any great extent.But UNAIDS and the HIV orthodoxy have, according to the article, been targeting the wrong people all along. They have been talking about reducing numbers of partners, using condoms and even giving up sex altogether. But many new infections occur in mutually monogamous couples, often among people who tak read more..

World Health Organization-Treatment Of Hiv-Hiv Prevention-HIV Infections-Effectiveness

Is an 'HIV Prevention Pill' Worth It?

Pre-exposure prophylaxis (PrEP) is an experimental method of HIV prevention. It involves a doctor prescribing antiretroviral HIV/AIDS drugs to a healthy person in order to prevent that person from possibly getting infected with HIV. So far, clinical trials have failed to prove PrEP’s effectiveness… (Click below to read more.)The 2007 iPrEX study found that PrEP reduced the risk of HIV infection among men who have sex with men (MSM) by only 44%. A part of the 2009 Vaginal and Oral Interventions to Control the Epidemic (VOICE) study was discontinued two years later because tenofovir (branded as Viread by Gilead Sciences) tablets were no better than a placebo in protecting HIV-negative women from HIV. Researchers stopped another trial in 2011, called Fem-PrEP, after they concluded that Truvada (Gilead’s combination tablet of tenofovir DF and emtricitabine) was unlikely to prevent HIV infection in women. Partners PrEP, a study of sero-discordant couples in Africa, showed an efficacy rate of 62%-73%. However it is imprudent to extrapolate the overall effectiveness of PrEP based of this study since the researchers reported an adherence rate of 95% among the study participants — a figure that would likely be much lower under non-clinical trial conditions and as a result, would likely lead to a lower overall efficacy rate.Questionable clinical efficacy aside, a surge in the interest around PrEP is puzzling given that 14.6 million HIV positive people around the world in need of ART right now are not receiving it. Expanding the permitted use of a lifesaving antiretroviral therapy—which is currently unavailable to those 14.6 million individuals still in need of treatment—as a sanctioned form of HIV prevention for use by uninfected individuals presents both a practical and moral dilemma for both Gilead and society at large.In the United States, the Centers for Disease Control and the Federal Drug Administration (FDA) have expressed interest in establishing guidelines for the use of PrEP. Under the current regulations, a medical provider is allowed to prescribe ART to a HIV negative person. This is called ‘off-label use’ – use of an HIV/AIDS medication for purposes other than treatment of HIV— effectively constitutes PrEP. However, as long as PrEP is not officially sanctioned by the FDA, drug companies cannot market ARTs as a preventative measure to the public. If PrEP is eventually approved by the FDA, pharmaceutical companies stand to make a lot of money catering to a new market in the developed world instead of providing cheaper—and much needed—drugs in the developing world.Internationally, PrEP has also received attention from the EU, the World Health Organization and various civil society organizations and advocates in the global health arena. The fact that PrEP is being considered as an evidence-based HIV prevention approach is incomprehensible at a time when the world cannot treat all people with HIV who are already ill.With the continued assault on generic drug manufacturers by Big Pharma and a stagnating commitment by the rich countries to contribute more money to the global AIDS fight, PrEP looks more like a pharmaceutical cash cow in the making, than a viable or prudent public health initiative. In the United States, one year of ART can cost upwards of $10,000 USD. Currently, there are waiting lists in the US for HIV-positive low-income people in need of treatment. In Eastern Europe, Central Asia and Africa ART coverage remains unacceptably low and far behind the Universal Access target of 80% for all who need it. Is it possible to justify giving PrEP to healthy people while the sick and dying are waiting for treatment?The legitimization of PrEP is detrimental because it could lead to a false sense of security among people who are currently using condoms to protect themselves. To achieve even a modest level of protection, PrEP requires strict adherence to a daily ART regime read more..